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Alzheimer’s Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci

Late onset Alzheimer’s disease (LOAD) is a genetically complex and clinically heterogeneous disease. Recent large-scale genome wide association studies (GWAS) have identified more than twenty loci that modify risk for AD. Despite the identification of these loci, little progress has been made in ide...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Karch, Celeste M., Ezerskiy, Lubov A., Bertelsen, Sarah, Goate, Alison M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769299/
https://ncbi.nlm.nih.gov/pubmed/26919393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148717
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