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Alzheimer’s-associated PU.1 expression levels regulate microglial inflammatory response
More than forty loci contribute to genetic risk for Alzheimer’s disease (AD). These risk alleles are enriched in myeloid cell enhancers suggesting that microglia, the brain-resident macrophages, contribute to AD risk. We have previously identified SPI1/PU.1, a master regulator of myeloid cell develo...
Tallennettuna:
| Julkaisussa: | Neurobiol Dis |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7808757/ https://ncbi.nlm.nih.gov/pubmed/33301878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105217 |
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