Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk

AKI with incomplete epithelial repair is a major contributor to CKD characterized by tubulointerstitial fibrosis. Injury–induced epithelial secretion of profibrotic factors is hypothesized to underlie this link, but the identity of these factors and whether epithelial injury is required remain undef...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Maarouf, Omar H., Aravamudhan, Anusha, Rangarajan, Deepika, Kusaba, Tetsuro, Zhang, Victor, Welborn, Jeremy, Gauvin, Daniel, Hou, Xiuyun, Kramann, Rafael, Humphreys, Benjamin D.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2016
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769196/
https://ncbi.nlm.nih.gov/pubmed/26204899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014121188
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