Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk

AKI with incomplete epithelial repair is a major contributor to CKD characterized by tubulointerstitial fibrosis. Injury–induced epithelial secretion of profibrotic factors is hypothesized to underlie this link, but the identity of these factors and whether epithelial injury is required remain undef...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Soc Nephrol
Egile Nagusiak: Maarouf, Omar H., Aravamudhan, Anusha, Rangarajan, Deepika, Kusaba, Tetsuro, Zhang, Victor, Welborn, Jeremy, Gauvin, Daniel, Hou, Xiuyun, Kramann, Rafael, Humphreys, Benjamin D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2016
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769196/
https://ncbi.nlm.nih.gov/pubmed/26204899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014121188
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