Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk

AKI with incomplete epithelial repair is a major contributor to CKD characterized by tubulointerstitial fibrosis. Injury–induced epithelial secretion of profibrotic factors is hypothesized to underlie this link, but the identity of these factors and whether epithelial injury is required remain undef...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Soc Nephrol
Prif Awduron: Maarouf, Omar H., Aravamudhan, Anusha, Rangarajan, Deepika, Kusaba, Tetsuro, Zhang, Victor, Welborn, Jeremy, Gauvin, Daniel, Hou, Xiuyun, Kramann, Rafael, Humphreys, Benjamin D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Nephrology 2016
Pynciau:
Basic Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769196/
https://ncbi.nlm.nih.gov/pubmed/26204899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014121188
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