Integrative Genomics Identifies Novel Associations with APOL1 Risk Genotypes in Black NEPTUNE Subjects

APOL1 variants have been associated with renal phenotypes in blacks. To refine clinical outcomes and discover mechanisms of APOL1-associated kidney injury, we analyzed clinical and genomic datasets derived from 90 black subjects in the Nephrotic Syndrome Study Network (NEPTUNE), stratified by APOL1...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Sampson, Matthew G., Robertson, Catherine C., Martini, Sebastian, Mariani, Laura H., Lemley, Kevin V., Gillies, Christopher E., Otto, Edgar A., Kopp, Jeffrey B., Randolph, Anne, Vega-Warner, Virginia, Eichinger, Felix, Nair, Viji, Gipson, Debbie S., Cattran, Daniel C., Johnstone, Duncan B., O’Toole, John F., Bagnasco, Serena M., Song, Peter X., Barisoni, Laura, Troost, Jonathan P., Kretzler, Matthias, Sedor, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769193/
https://ncbi.nlm.nih.gov/pubmed/26150607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014111131
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