TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1

TRAF2 is a component of TNF superfamily signalling complexes and plays an essential role in the regulation and homeostasis of immune cells. TRAF2 deficient mice die around birth, therefore its role in adult tissues is not well-explored. Furthermore, the role of the TRAF2 RING is controversial. It ha...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Etemadi, Nima, Chopin, Michael, Anderton, Holly, Tanzer, Maria C, Rickard, James A, Abeysekera, Waruni, Hall, Cathrine, Spall, Sukhdeep K, Wang, Bing, Xiong, Yuquan, Hla, Timothy, Pitson, Stuart M, Bonder, Claudine S, Wong, Wendy Wei-Lynn, Ernst, Matthias, Smyth, Gordon K, Vaux, David L, Nutt, Stephen L, Nachbur, Ueli, Silke, John
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2015
Onderwerpen:
Biochemistry
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769158/
https://ncbi.nlm.nih.gov/pubmed/26701909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10592
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items