TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1

TRAF2 is a component of TNF superfamily signalling complexes and plays an essential role in the regulation and homeostasis of immune cells. TRAF2 deficient mice die around birth, therefore its role in adult tissues is not well-explored. Furthermore, the role of the TRAF2 RING is controversial. It ha...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:eLife
Κύριοι συγγραφείς: Etemadi, Nima, Chopin, Michael, Anderton, Holly, Tanzer, Maria C, Rickard, James A, Abeysekera, Waruni, Hall, Cathrine, Spall, Sukhdeep K, Wang, Bing, Xiong, Yuquan, Hla, Timothy, Pitson, Stuart M, Bonder, Claudine S, Wong, Wendy Wei-Lynn, Ernst, Matthias, Smyth, Gordon K, Vaux, David L, Nutt, Stephen L, Nachbur, Ueli, Silke, John
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: eLife Sciences Publications, Ltd 2015
Θέματα:
Biochemistry
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769158/
https://ncbi.nlm.nih.gov/pubmed/26701909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10592
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