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Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis

Given the ability of M. tuberculosis to survive as an intracellular pathogen and its propensity to develop resistance to the existing antituberculosis drugs, its treatment requires new approaches. Here the antimycobacterial properties of verapamil, thioridazine, chlorpromazine, flupenthixol and halo...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Machado, Diana, Pires, David, Perdigão, João, Couto, Isabel, Portugal, Isabel, Martins, Marta, Amaral, Leonard, Anes, Elsa, Viveiros, Miguel
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769142/
https://ncbi.nlm.nih.gov/pubmed/26919135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149326
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