Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis

Given the ability of M. tuberculosis to survive as an intracellular pathogen and its propensity to develop resistance to the existing antituberculosis drugs, its treatment requires new approaches. Here the antimycobacterial properties of verapamil, thioridazine, chlorpromazine, flupenthixol and halo...

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Publicat a:PLoS One
Autors principals: Machado, Diana, Pires, David, Perdigão, João, Couto, Isabel, Portugal, Isabel, Martins, Marta, Amaral, Leonard, Anes, Elsa, Viveiros, Miguel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769142/
https://ncbi.nlm.nih.gov/pubmed/26919135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149326
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