Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis

Given the ability of M. tuberculosis to survive as an intracellular pathogen and its propensity to develop resistance to the existing antituberculosis drugs, its treatment requires new approaches. Here the antimycobacterial properties of verapamil, thioridazine, chlorpromazine, flupenthixol and halo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Machado, Diana, Pires, David, Perdigão, João, Couto, Isabel, Portugal, Isabel, Martins, Marta, Amaral, Leonard, Anes, Elsa, Viveiros, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769142/
https://ncbi.nlm.nih.gov/pubmed/26919135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149326
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