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Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype.

The phenotype of the transforming growth factor beta 1 (TGF-beta 1) null mouse has been previously described and is characterized by inflammatory infiltrates in multiple organs leading to a wasting syndrome and death as early as 3 weeks after birth. Since this phenotype occurs in the absence of any...

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Bibliographic Details
Main Authors: Geiser, A G, Letterio, J J, Kulkarni, A B, Karlsson, S, Roberts, A B, Sporn, M B
Format: Artigo
Language:Inglês
Published: 1993
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC47689/
https://ncbi.nlm.nih.gov/pubmed/8234339
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