Secreted frizzled related protein 3 (SFRP3) is required for tumorigenesis of PAX3-FOXO1-positive alveolar rhabdomyosarcoma

PURPOSE: Rhabdomyosarcoma is a soft tissue sarcoma associated with the skeletal muscle lineage. Of the two predominant subtypes, known as embryonal (eRMS) and alveolar (aRMS), aRMS has the poorer prognosis, with a 5-year survival rate of <50%. The majority of aRMS tumors express the fusion protei...

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Опубликовано в: :Clin Cancer Res
Главные авторы: Kephart, Julie J.G., Tiller, Rosanne G.J., Crose, Lisa E.S., Slemmons, Katherine K., Chen, Po-Han, Hinson, Ashley R., Bentley, Rex C., Chi, Jen-Tsan Ashley, Linardic, Corinne M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768793/
https://ncbi.nlm.nih.gov/pubmed/26071485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1797
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