The combined effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and the phytoestrogen genistein on steroid hormone secretion, AhR and ERβ expression and the incidence of apoptosis in granulosa cells of medium porcine follicles

Low doses of endocrine disrupting chemicals (EDCs) used in combination may act in a manner different from that of individual compounds. The objective of the study was to examine in vitro effects of low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; 100 pM) and genistein (500 nM) on: 1) progeste...

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Veröffentlicht in:J Reprod Dev
Hauptverfasser: PIASECKA-SRADER, Joanna, SADOWSKA, Agnieszka, NYNCA, Anna, ORLOWSKA, Karina, JABLONSKA, Monika, JABLONSKA, Olga, PETROFF, Brian K., CIERESZKO, Renata E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Society for Reproduction and Development 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768784/
https://ncbi.nlm.nih.gov/pubmed/26568065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2015-125
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