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The combined effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and the phytoestrogen genistein on steroid hormone secretion, AhR and ERβ expression and the incidence of apoptosis in granulosa cells of medium porcine follicles

Low doses of endocrine disrupting chemicals (EDCs) used in combination may act in a manner different from that of individual compounds. The objective of the study was to examine in vitro effects of low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; 100 pM) and genistein (500 nM) on: 1) progeste...

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Detalhes bibliográficos
Publicado no:J Reprod Dev
Main Authors: PIASECKA-SRADER, Joanna, SADOWSKA, Agnieszka, NYNCA, Anna, ORLOWSKA, Karina, JABLONSKA, Monika, JABLONSKA, Olga, PETROFF, Brian K., CIERESZKO, Renata E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Reproduction and Development 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768784/
https://ncbi.nlm.nih.gov/pubmed/26568065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2015-125
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