Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin.

Endotoxin stimulates leukocytes to release cytokines that initiate septic shock in humans and animals. CD14, a glycosyl-phosphatidylinositol-anchored membrane glycoprotein, is an endotoxin receptor on leukocytes, and endotoxin binding to CD14 induces cytokine production. Here we show that glycosyl-p...

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Detalhes bibliográficos
Main Authors: Lee, J D, Kravchenko, V, Kirkland, T N, Han, J, Mackman, N, Moriarty, A, Leturcq, D, Tobias, P S, Ulevitch, R J
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47686/
https://ncbi.nlm.nih.gov/pubmed/7694296
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