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Zfrp8 forms a complex with Fragile-X Mental Retardation Protein and regulates its localization and function
Fragile-X syndrome is the most commonly inherited cause of autism and mental disabilities. The Fmr1 (Fragile-X Mental Retardation 1) gene is essential in humans and Drosophila for the maintenance of neural stem cells, and Fmr1 loss results in neurological and reproductive developmental defects in hu...
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| Veröffentlicht in: | Dev Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4768487/ https://ncbi.nlm.nih.gov/pubmed/26772998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.12.008 |
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