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Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes
BACKGROUND: Endogenous defense against oxidative stress is controlled by nuclear factor erythroid 2-related factor 2 (Nrf2). The normal compensatory mechanisms to combat oxidative stress appear to be insufficient to protect against the prolonged exposure to reactive oxygen species during disease. Co...
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| Veröffentlicht in: | J Neuroinflammation |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4768425/ https://ncbi.nlm.nih.gov/pubmed/26920699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0515-9 |
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