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Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448

BACKGROUND: Triple negative breast cancers (TNBC) possess cell dedifferentiation characteristics, carry out activities connate to those of cancer stem cells (CSCs) and are associated with increased metastasis, as well as, poor clinical prognosis. The regulatory mechanism of this highly malignant phe...

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Bibliografische gegevens
Gepubliceerd in:BMC Cancer
Hoofdauteurs: Bamodu, Oluwaseun Adebayo, Huang, Wen-Chien, Lee, Wei-Hwa, Wu, Alexander, Wang, Liang Shun, Hsiao, Michael, Yeh, Chi-Tai, Chao, Tsu-Yi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768424/
https://ncbi.nlm.nih.gov/pubmed/26917489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2108-5
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