Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448

BACKGROUND: Triple negative breast cancers (TNBC) possess cell dedifferentiation characteristics, carry out activities connate to those of cancer stem cells (CSCs) and are associated with increased metastasis, as well as, poor clinical prognosis. The regulatory mechanism of this highly malignant phe...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Bamodu, Oluwaseun Adebayo, Huang, Wen-Chien, Lee, Wei-Hwa, Wu, Alexander, Wang, Liang Shun, Hsiao, Michael, Yeh, Chi-Tai, Chao, Tsu-Yi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768424/
https://ncbi.nlm.nih.gov/pubmed/26917489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2108-5
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