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Dose modifications in Asian cancer patients with hepatic dysfunction receiving weekly docetaxel: A prospective pharmacokinetic and safety study

Hepatic dysfunction may modify the safety profile and pharmacokinetics of docetaxel in cancer patients, but no validated guideline exists to guide dose modification necessitated by this uncommon comorbidity. We carried out the first prospective study of a personalized dosage regimen for cancer patie...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Syn, Nicholas Li‐Xun, Wang, Lingzhi, Wong, Andrea Li‐Ann, Soe, Mu‐Yar, Chuah, Benjamin, Chan, Daniel, Tan, Sing‐Huang, Soo, Ross Andrew, Lee, Soo‐Chin, Goh, Boon‐Cher, Yong, Wei‐Peng
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768392/
https://ncbi.nlm.nih.gov/pubmed/26663719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12856
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