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Dose modifications in Asian cancer patients with hepatic dysfunction receiving weekly docetaxel: A prospective pharmacokinetic and safety study

Hepatic dysfunction may modify the safety profile and pharmacokinetics of docetaxel in cancer patients, but no validated guideline exists to guide dose modification necessitated by this uncommon comorbidity. We carried out the first prospective study of a personalized dosage regimen for cancer patie...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Syn, Nicholas Li‐Xun, Wang, Lingzhi, Wong, Andrea Li‐Ann, Soe, Mu‐Yar, Chuah, Benjamin, Chan, Daniel, Tan, Sing‐Huang, Soo, Ross Andrew, Lee, Soo‐Chin, Goh, Boon‐Cher, Yong, Wei‐Peng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768392/
https://ncbi.nlm.nih.gov/pubmed/26663719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12856
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