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Receptor tyrosine kinase‐like orphan receptor 1, a target of NKX2‐1/TTF‐1 lineage‐survival oncogene, inhibits apoptosis signal‐regulating kinase 1‐mediated pro‐apoptotic signaling in lung adenocarcinoma
We previously identified receptor tyrosine kinase‐like orphan receptor 1 (ROR1) as a transcriptional target of the NKX2‐1/TTF‐1 lineage‐survival oncogene in lung adenocarcinoma. ROR1 consequently sustains a favorable balance between pro‐survival phosphatidylinositol 3‐kinase–protein kinase B and pro...
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| Publicado no: | Cancer Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4768386/ https://ncbi.nlm.nih.gov/pubmed/26661061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12858 |
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