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The positive frequency-dependent electrophysiological effects of the I(Kur) inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation
BACKGROUND: Selective inhibitors of K(v)1.5 channels are being developed for the treatment of atrial fibrillation (AF). OBJECTIVES: The purpose of this study was to investigate the effects of the highly selective K(v)1.5 inhibitor XEN-D0103 on human atrial action potentials (APs) at high excitation...
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| 發表在: | Heart Rhythm |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4768384/ https://ncbi.nlm.nih.gov/pubmed/26455450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2015.10.003 |
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