The STIM1-Orai1 pathway of store-operated Ca(2+) entry controls the checkpoint in cell cycle G1/S transition

Ca(2+) signaling is important to trigger the cell cycle progression, while it remains elusive in the regulatory mechanisms. Here we show that store-operated Ca(2+) entry (SOCE), mediated by the interaction between STIM1 (an endoplasmic reticulum Ca(2+) sensor) and Orai1 (a cell membrane pore structu...

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Udgivet i:Sci Rep
Main Authors: Chen, Yun-Wen, Chen, Yih-Fung, Chen, Ying-Ting, Chiu, Wen-Tai, Shen, Meng-Ru
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768259/
https://ncbi.nlm.nih.gov/pubmed/26917047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22142
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