High levels of homocysteine downregulate apolipoprotein E expression via nuclear factor kappa B

AIM: To investigate the effect of high homocysteine (Hcy) levels on apolipoprotein E (apoE) expression and the signaling pathways involved in this gene regulation. METHODS: Reverse transcriptase polymerase chain reaction (RT-PCR) and Western blot were used to assess apoE expression in cells treated...

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Vydáno v:World J Biol Chem
Hlavní autoři: Trusca, Violeta G, Mihai, Adina D, Fuior, Elena V, Fenyo, Ioana M, Gafencu, Anca V
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Inc 2016
Témata:
Basic Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768122/
https://ncbi.nlm.nih.gov/pubmed/26981206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v7.i1.178
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