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IL‐6 and IL‐17A degradation by mast cells is mediated by a serglycin:serine protease axis

Mast cells contain large amounts of fully active proteases that are stored in complex with serglycin proteoglycan in their secretory granules. Upon degranulation, such serglycin:protease complexes are released to the extracellular space and can potentially have an impact on the local inflammatory re...

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Bibliografische gegevens
Gepubliceerd in:Immun Inflamm Dis
Hoofdauteurs: Waern, Ida, Karlsson, Iulia, Pejler, Gunnar, Wernersson, Sara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768062/
https://ncbi.nlm.nih.gov/pubmed/27042303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.95
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