Antisense inhibition of the p65 subunit of NF-kappa B blocks tumorigenicity and causes tumor regression.

The NF-kappa B transcription factor, composed of two proteins, p50 and p65, is a pleiotropic activator that participates in the induction of a wide variety of cellular genes. Various cell adhesion molecules have NF-kappa B binding sites and may play an important role in inflammatory response, tumori...

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Bibliographic Details
Main Authors: Higgins, K A, Perez, J R, Coleman, T A, Dorshkind, K, McComas, W A, Sarmiento, U M, Rosen, C A, Narayanan, R
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC47680/
https://ncbi.nlm.nih.gov/pubmed/8234333
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