Antisense inhibition of the p65 subunit of NF-kappa B blocks tumorigenicity and causes tumor regression.

The NF-kappa B transcription factor, composed of two proteins, p50 and p65, is a pleiotropic activator that participates in the induction of a wide variety of cellular genes. Various cell adhesion molecules have NF-kappa B binding sites and may play an important role in inflammatory response, tumori...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Higgins, K A, Perez, J R, Coleman, T A, Dorshkind, K, McComas, W A, Sarmiento, U M, Rosen, C A, Narayanan, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47680/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8234333/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.21.9901
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