Forkhead box K2 modulates epirubicin and paclitaxel sensitivity through FOXO3a in breast cancer

The forkhead transcription factor FOXK2 has recently been implicated in cancer cell proliferation and survival, but a role in cancer chemotherapeutic drug resistance has hitherto not been explored. Here we demonstrate that FOXK2 has a central role in mediating the cytotoxic drug response in breast c...

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Udgivet i:Oncogenesis
Main Authors: de Moraes, G Nestal, Khongkow, P, Gong, C, Yao, S, Gomes, A R, Ji, Z, Kandola, N, Delbue, D, Man, E P S, Khoo, U S, Sharrocks, A D, Lam, E W-F
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767938/
https://ncbi.nlm.nih.gov/pubmed/26344694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2015.26
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