Hypoxia and Hypoxia-Inducible Factors in Leukemias

Despite huge improvements in the treatment of leukemia, the percentage of patients suffering relapse still remains significant. Relapse most often results from a small number of leukemic stem cells (LSCs) within the bone marrow, which are able to self-renew, and therefore reestablish the full tumor....

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Bibliographic Details
Published in:Front Oncol
Main Authors: Deynoux, Margaux, Sunter, Nicola, Hérault, Olivier, Mazurier, Frédéric
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767894/
https://ncbi.nlm.nih.gov/pubmed/26955619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00041
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