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Extracellular vesicles activate a CD36 dependent signaling pathway to inhibit microvascular endothelial cell migration and tube formation

OBJECTIVE: Literature on the effect of cell-derived extracellular vesicles (EV), ≤1μm vesicles shed from various cell types during activation or apoptosis, on microvascular endothelial cell (MVEC) signaling is conflicting. Thrombospondin-1 and related proteins induce anti-angiogenic signals in MVEC...

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Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Ramakrishnan, Devi Prasadh, Hajj-Ali, Rula A., Chen, Yiliang, Silverstein, Roy L.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767682/
https://ncbi.nlm.nih.gov/pubmed/26821945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.307085
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