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Hydrogels with tunable stress relaxation regulate stem cell fate and activity

Natural extracellular matrices (ECMs) are viscoelastic and exhibit stress relaxation. However, hydrogels used as synthetic ECMs for three-dimensional (3D) culture are typically elastic. Here, we report a materials approach to tune the rate of stress relaxation of hydrogels for 3D culture, independen...

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Detalhes bibliográficos
Publicado no:Nat Mater
Main Authors: Chaudhuri, Ovijit, Gu, Luo, Klumpers, Darinka, Darnell, Max, Bencherif, Sidi A., Weaver, James C., Huebsch, Nathaniel, Lee, Hong-pyo, Lippens, Evi, Duda, Georg N., Mooney, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767627/
https://ncbi.nlm.nih.gov/pubmed/26618884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4489
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