High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

Systemic lupus erythematosus (SLE) has a strong but incompletely understood genetic architecture. We conducted an association study with replication in 4,492 SLE cases and 12,675 controls from six East-Asian cohorts, to identify novel and better localize known SLE susceptibility loci. We identified...

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Publicado no:Nat Genet
Main Authors: Sun, Celi, Molineros, Julio E., Looger, Loren L., Zhou, Xu-jie, Kim, Kwangwoo, Okada, Yukinori, Ma, Jianyang, Qi, Yuan-yuan, Kim-Howard, Xana, Motghare, Prasenjeet, Bhattarai, Krishna, Adler, Adam, Bang, So-Young, Lee, Hye-Soon, Kim, Tae-Hwan, Kang, Young Mo, Suh, Chang-Hee, Chung, Won Tae, Park, Yong-Beom, Choe, Jung-Yoon, Shim, Seung Cheol, Kochi, Yuta, Suzuki, Akari, Kubo, Michiaki, Sumida, Takayuki, Yamamoto, Kazuhiko, Lee, Shin-Seok, Kim, Young Jin, Han, Bok-Ghee, Dozmorov, Mikhail, Kaufman, Kenneth M., Wren, Jonathan D., Harley, John B., Shen, Nan, Chua, Kek Heng, Zhang, Hong, Bae, Sang-Cheol, Nath, Swapan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767573/
https://ncbi.nlm.nih.gov/pubmed/26808113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3496
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