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Identification of regions within the Legionella pneumophila VipA effector protein involved in actin binding and polymerization and in interference with eukaryotic organelle trafficking

The Legionella pneumophila effector protein VipA is an actin nucleator that co‐localizes with actin filaments and early endosomes in infected macrophages and which interferes with organelle trafficking when expressed in yeast. To identify the regions of VipA involved in its subcellular localization...

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Publicat a:Microbiologyopen
Autors principals: Bugalhão, Joana N., Mota, Luís Jaime, Franco, Irina S.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767423/
https://ncbi.nlm.nih.gov/pubmed/26626407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.316
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