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Identification of regions within the Legionella pneumophila VipA effector protein involved in actin binding and polymerization and in interference with eukaryotic organelle trafficking

The Legionella pneumophila effector protein VipA is an actin nucleator that co‐localizes with actin filaments and early endosomes in infected macrophages and which interferes with organelle trafficking when expressed in yeast. To identify the regions of VipA involved in its subcellular localization...

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Detalhes bibliográficos
Publicado no:Microbiologyopen
Main Authors: Bugalhão, Joana N., Mota, Luís Jaime, Franco, Irina S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767423/
https://ncbi.nlm.nih.gov/pubmed/26626407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.316
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