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Dopamine D1 receptor activation improves PCP-induced performance disruption in the 5C-CPT by reducing inappropriate responding

Attentional deficits contribute significantly to the functional disability of schizophrenia patients. The 5-choice continuous performance test (5C-CPT) measures attention in mice, rats, and humans, requiring the discrimination of trial types that either require a response or the inhibition of a resp...

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Pubblicato in:Behav Brain Res
Autori principali: Barnes, S.A., Young, J.W., Bate, S.T., Neill, J.C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767402/
https://ncbi.nlm.nih.gov/pubmed/26658514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2015.11.035
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