Rats tested after a washout period from sub-chronic PCP administration exhibited impaired performance in the 5-choice continuous performance test (5C-CPT) when the attentional load was increased

It is well documented that schizophrenia patients exhibit dysfunction in various cognitive domains, including attention/vigilance, as demonstrated by impaired performance in the myriad of continuous performance tests (CPTs). NMDA receptor antagonists provide a pharmacological model in animals of the...

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Veröffentlicht in:Neuropharmacology
Hauptverfasser: BARNES, Samuel A, YOUNG, Jared W, NEILL, Jo C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870141/
https://ncbi.nlm.nih.gov/pubmed/21569782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.04.024
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