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Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis

The development of the hematopoietic system is a dynamic process that is controlled by the interplay between transcriptional and epigenetic networks to determine cellular identity. These networks are critical for lineage specification and are frequently dysregulated in leukemias. Here, we identified...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Andricovich, Jaclyn, Kai, Yan, Peng, Weiqun, Foudi, Adlen, Tzatsos, Alexandros
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767361/
https://ncbi.nlm.nih.gov/pubmed/26808549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84014
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