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Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis

The development of the hematopoietic system is a dynamic process that is controlled by the interplay between transcriptional and epigenetic networks to determine cellular identity. These networks are critical for lineage specification and are frequently dysregulated in leukemias. Here, we identified...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Andricovich, Jaclyn, Kai, Yan, Peng, Weiqun, Foudi, Adlen, Tzatsos, Alexandros
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767361/
https://ncbi.nlm.nih.gov/pubmed/26808549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84014
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