Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy

Abnormalities of cardiomyocyte Ca(2 +) homeostasis and excitation–contraction (E–C) coupling are early events in the pathogenesis of hypertrophic cardiomyopathy (HCM) and concomitant determinants of the diastolic dysfunction and arrhythmias typical of the disease. T-tubule remodelling has been repor...

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Publicado en:J Mol Cell Cardiol
Main Authors: Crocini, C., Ferrantini, C., Scardigli, M., Coppini, R., Mazzoni, L., Lazzeri, E., Pioner, J.M., Scellini, B., Guo, A., Song, L.S., Yan, P., Loew, L.M., Tardiff, J., Tesi, C., Vanzi, F., Cerbai, E., Pavone, F.S., Sacconi, L., Poggesi, C.
Formato: Artigo
Idioma:Inglês
Publicado: Academic Press 2016
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767219/
https://ncbi.nlm.nih.gov/pubmed/26714042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.12.013
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