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Trimming of sequence reads alters RNA-Seq gene expression estimates

BACKGROUND: High-throughput RNA-Sequencing (RNA-Seq) has become the preferred technique for studying gene expression differences between biological samples and for discovering novel isoforms, though the techniques to analyze the resulting data are still immature. One pre-processing step that is wide...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Williams, Claire R., Baccarella, Alyssa, Parrish, Jay Z., Kim, Charles C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766705/
https://ncbi.nlm.nih.gov/pubmed/26911985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0956-2
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