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Trimming of sequence reads alters RNA-Seq gene expression estimates

BACKGROUND: High-throughput RNA-Sequencing (RNA-Seq) has become the preferred technique for studying gene expression differences between biological samples and for discovering novel isoforms, though the techniques to analyze the resulting data are still immature. One pre-processing step that is wide...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Williams, Claire R., Baccarella, Alyssa, Parrish, Jay Z., Kim, Charles C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766705/
https://ncbi.nlm.nih.gov/pubmed/26911985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0956-2
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