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Trimming of sequence reads alters RNA-Seq gene expression estimates

BACKGROUND: High-throughput RNA-Sequencing (RNA-Seq) has become the preferred technique for studying gene expression differences between biological samples and for discovering novel isoforms, though the techniques to analyze the resulting data are still immature. One pre-processing step that is wide...

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Détails bibliographiques
Publié dans:BMC Bioinformatics
Auteurs principaux: Williams, Claire R., Baccarella, Alyssa, Parrish, Jay Z., Kim, Charles C.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766705/
https://ncbi.nlm.nih.gov/pubmed/26911985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0956-2
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