Niclosamide induced cell apoptosis via upregulation of ATF3 and activation of PERK in Hepatocellular carcinoma cells

BACKGROUND: Hepatocellular carcinoma (HCC) is one of most common and aggressive human malignancies in the world, especially, in eastern Asia, and its mortality is very high at any phase. We want to investigate mechanism of niclosamide inducing cell apoptosis in HCC. METHODS: Two hepatoma cell lines...

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Bibliografske podrobnosti
izdano v:BMC Gastroenterol
Main Authors: Weng, Shunyan, Zhou, Liang, Deng, Qing, Wang, Jiaxian, Yu, Yan, Zhu, Jianwei, Yuan, Yunsheng
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766699/
https://ncbi.nlm.nih.gov/pubmed/26917416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-016-0442-3
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