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Fluorinated betulinic acid derivatives and evaluation of their anti-HIV activity
Several fluorinated derivatives of the anti-HIV maturation agent bevirimat (1) were synthesized and evaluated for anti-HIV replication activity. The modified positions were the C-2, C-3, C-28, and C-30 positions, either directly on the betulinic acid (2) skeleton or in the attached side chains. Comp...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4766590/ https://ncbi.nlm.nih.gov/pubmed/26598461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.11.029 |
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