The Synthetic Tie2 Agonist Peptide Vasculotide Protects Renal Vascular Barrier Function In Experimental Acute Kidney Injury

Microvascular barrier dysfunction plays a major role in the pathophysiology of acute kidney injury (AKI). Angiopoietin-1, the natural agonist ligand for the endothelial-specific Tie2 receptor, is a non-redundant endothelial survival and vascular stabilization factor. Here we evaluate the efficacy of...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Rübig, Eva, Stypmann, Jörg, Van Slyke, Paul, Dumont, Daniel J, Spieker, Tilmann, Buscher, Konrad, Reuter, Stefan, Goerge, Tobias, Pavenstädt, Hermann, Kümpers, Philipp
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766468/
https://ncbi.nlm.nih.gov/pubmed/26911791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22111
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