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Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality
A synthetic 7-mer, HHHRHSF, was recently identified by screening a phage display library for binding to the Tie-2 receptor. A polyethylene-oxide clustered version of this peptide, termed vasculotide (VT), was reported to activate Tie-2 and promote angiogenesis in a mouse model of diabetic ulcer. We...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119126/ https://ncbi.nlm.nih.gov/pubmed/21421750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00459.2010 |
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