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Visualization and quantification of deformation behavior of clopidogrel bisulfate polymorphs during tableting
The deformation behavior of particles under pressure dominates the mechanical properties of solid dosage forms. In this study, the in situ 3D deformation of two polymorphs (I and II) of clopidogrel bisulfate (CLP) was determined to illustrate pressure distribution profiles within the tablet by the d...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4766417/ https://ncbi.nlm.nih.gov/pubmed/26911359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21770 |
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