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D-Serine and Serine Racemase Are Associated with PSD-95 and Glutamatergic Synapse Stability
D-serine is an endogenous coagonist at the glycine site of synaptic NMDA receptors (NMDARs), synthesized by serine racemase (SR) through conversion of L-serine. It is crucial for synaptic plasticity and is implicated in schizophrenia. Our previous studies demonstrated specific loss of SR, D-serine-r...
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| Udgivet i: | Front Cell Neurosci |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4766304/ https://ncbi.nlm.nih.gov/pubmed/26941605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00034 |
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