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Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review
BACKGROUND: Personalized medicine is a growing area of research which aims to tailor the treatment given to a patient according to one or more personal characteristics. These characteristics can be demographic such as age or gender, or biological such as a genetic or other biomarker. Prior to utiliz...
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| Publicado no: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4766245/ https://ncbi.nlm.nih.gov/pubmed/26910238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149803 |
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