Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice

The cardiac hormone atrial natriuretic peptide (ANP) regulates systemic and pulmonary arterial blood pressure by activation of its cyclic GMP-producing guanylyl cyclase-A (GC-A) receptor. In the lung, these hypotensive effects were mainly attributed to smooth muscle-mediated vasodilatation. It is un...

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Bibliografiske detaljer
Udgivet i:Basic Res Cardiol
Main Authors: Werner, Franziska, Kojonazarov, Baktybek, Gaßner, Birgit, Abeßer, Marco, Schuh, Kai, Völker, Katharina, Baba, Hideo A., Dahal, Bhola K., Schermuly, Ralph T., Kuhn, Michaela
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2016
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Original Contribution
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766231/
https://ncbi.nlm.nih.gov/pubmed/26909880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-016-0541-x
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