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Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice

The cardiac hormone atrial natriuretic peptide (ANP) regulates systemic and pulmonary arterial blood pressure by activation of its cyclic GMP-producing guanylyl cyclase-A (GC-A) receptor. In the lung, these hypotensive effects were mainly attributed to smooth muscle-mediated vasodilatation. It is un...

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Detalhes bibliográficos
Publicado no:Basic Res Cardiol
Main Authors: Werner, Franziska, Kojonazarov, Baktybek, Gaßner, Birgit, Abeßer, Marco, Schuh, Kai, Völker, Katharina, Baba, Hideo A., Dahal, Bhola K., Schermuly, Ralph T., Kuhn, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766231/
https://ncbi.nlm.nih.gov/pubmed/26909880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-016-0541-x
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